Resistance to Anti-Cancer Therapeutics Targeting Receptor Tyrosine Kinases and Downstream Pathways


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Author(s): Yosef Yarden, Moshe Elkabets

Series: Resistance to Targeted Anti-Cancer Therapeutics 15

Publisher: Springer International Publishing, Year: 2018

ISBN: 978-3-319-67930-3,978-3-319-67932-7

This volume comprehensively covers the multiplicity and diversity of mechanisms underlying patient resistance to currently approved anti-cancer drugs, including tyrosine kinase inhibitors and monoclonal antibodies, blockers of growth factor receptors and their downstream pathways, which play essential functions in cancer progression. Each chapter will cover a specific group of targets and the cognate drugs, along with molecular modes of innate and evolving resistance.

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