Notch signaling : immunity and cancer


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Author(s): Yasutomo, Koji

Publisher: Springer, Year: 2017

ISBN: 978-981-10-4971-2,9811049718,978-981-10-4970-5

This book covers the broad area related to Notch-mediated regulation of the immune system and tumorigenesis. Notch signaling was originally identified as a crucial pathway to regulate cell fate choice. Subsequent studies, however, have revealed that Notch regulates many steps of immune cell differentiation or development as well as tumorigenesis of cells. Although there are still many controversial issues regarding Read more…


Also, the studies regarding the functions of Notch in immune cells and tumor cells have motivated researchers and pharmaceutical companies to develop drugs for treating immune-mediated diseases and Read more…

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