Ex Vivo Engineering of the Tumor Microenvironment

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Author(s): Amir R. Aref, David Barbie (eds.)

Series: Cancer Drug Discovery and Development

Publisher: Humana Press, Year: 2017

ISBN: 978-3-319-45395-8, 978-3-319-45397-2

Description:This volume will outline how to recreate the tumor microenvironment, to culture primary tumors without the need for developmental priming factors, and to deliver targeted therapeutics in a manner that recapitulates pharmacokinetics in vivo. Much of what may be learned from this volume will aid in understanding many aspects of the enhanced study of tumor cell biology in a physiologic context, open new avenues for drug screening and biomarker development, and accelerate the preclinical evaluation of novel personalized medicine strategies for patients in real time.

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