Advancing Gene Fusion Detection Towards Personalized Cancer Nanodiagnostics


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Author(s): Kevin M. Koo

Series: Springer Theses

Publisher: Springer International Publishing, Year: 2019

ISBN: 978-3-030-30999-2,978-3-030-31000-4


This book presents a unique concept of merging nanotechnology and novel urinary biomarkers for accurate early prostate cancer detection, discussing an entire progressive pipeline of innovative new strategies in biosensor development, from a simple colorimetric system to a complex system for simultaneous multiple biomarker sensing. For newcomers to the field of nucleic acid biosensing, it also describes various isothermal amplification and amplification-free strategies, which are currently the main research areas. Lastly, the book introduces and demonstrates the notion of clinical nanobiosensor validation toward clinical translation: the ultimate aim of researchers in the biosensor field. This book is a valuable reference resource learners seeking inspiration for cancer biosensor development.

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